I just purchased fpse for android and this is the first game I'm trying. I have the US bios (scph1001.bin) loaded properly (I see the sony logo) and the image I have is in bin/cue format. I haven't modified the cue file but I don't believe that's necessary.

I get the initial loading menu and select start game and then get the fmv intro, skipping that I'm brought to the first scene of gameplay but it's frozen.

I read for this game invertcolors option is needed which I have selected, but the same thing.

I also tried with the opengl plugin (even though this particular game is 3d) but same as well.
I'm on a stock nexus 7.

I've read this game works so I'm not sure what else I need to do or if this is an issue with the latest version of fpse.

I got it working by info in this other thread:

http://www.fpsece.net/forum2/viewtopic.php?f=39&t=2664&hilit=heart+of+darkness

Enabling spu sync. I read this before, but it didn't seem to take unless I save the setting as the default and reload. Does this setting affect other games and am I correct taht settings must be saved to take effect?

Also this other thread says he couldn't switch to disc 2. Does this support multi-disc games or is it an issue with heart of darkness?

I don't know if the issue with multi-disk is game-specific or not. I do know fpse support multidisk - you just choose change disk and restart. but, some people have reported issues with some games.

I bit of advice - don't rely on save states. be sure to use the in games saves as well. Save states usually work - but sometimes they fail. don't rely on them.

multi disk is fixed since somes release. should work now.